CBIO Historical PE Ratio image Crescent Biopharma Historical PE Ratio

This CBIO historical PE ratio page, which was last updated 7/31/2026, presents historical price to earnings information for Crescent Biopharma under both the TTM method and the annualized method, and presented in both tabular and graphical format for ease of study.

CBIO Historical PE Ratio Notes

— Crescent Biopharma (“CBIO”) is a biotechnology company focused on developing innovative therapies for diseases with significant unmet medical needs, primarily in the rare disease & immunotherapy space. The company's product pipeline typically consists of early- to mid-stage clinical candidates, and Crescent Biopharma often reinvests earnings into research & development to advance its drug candidates through costly clinical trials. As a result, CBIO's reported earnings fluctuate significantly based on trial progress, licensing deals, and milestone payments rather than steady commercial sales. This business model means Crescent Biopharma's historical PE (price-to-earnings) ratio may exhibit considerable volatility, and in some years, the ratio may not be meaningful (or even calculable) during periods of operating losses. When reviewing CBIO's historical PE ratio along with price & earnings data, investors should consider not just absolute values, but also the context: periods of negative earnings, one-time partnership revenue, or shifts in the company's strategic focus can all impact the numerator or denominator of the PE ratio. For biopharma companies like CBIO, changes in PE over time often reflect investor sentiment about future drug approvals or commercialization prospects, rather than current profitability.
CBIO Historical PE Ratio Chart
PeriodPriceGAAPAnnualizedPE
Q2 2026
7/30/2026
15.02-0.74-2.96NA
Q1 2026
4/29/2026
20.94-0.70-2.80NA
Q4 2025
2/26/2026
12.35-4.01-16.04NA
Q3 2025
11/6/2025
13.10-1.27-5.08NA
Q2 2025
7/31/2025
12.42-4.93-19.72NA
Q3 2022
11/14/2022
145.00-0.16-0.64NA
Q2 2022
8/15/2022
84.00-0.18-0.72NA
Q1 2022
5/9/2022
62.00-0.46-1.84NA
Q4 2021
3/31/2022
114.00-0.65-2.60NA
Q3 2021
11/12/2021
213.00-0.80-3.20NA
Q2 2021
8/5/2021
215.00-0.64-2.56NA
Q1 2021
5/6/2021
230.00-0.79-3.16NA
Q4 2020
3/4/2021
297.00-0.86-3.44NA
Q3 2020
11/5/2020
305.00-0.73-2.92NA
Q2 2020
8/6/2020
388.00-0.96-3.84NA
Q1 2020
5/11/2020
313.00-0.28-1.12NA
Q4 2019
2/20/2020
421.00-1.23-4.92NA
Q3 2019
11/7/2019
596.00-1.06-4.24NA
Q2 2019
8/1/2019
925.00-1.15-4.60NA
Q1 2019
5/2/2019
1194.00-1.26-5.04NA
Q4 2018
3/7/2019
1101.00-0.91-3.64NA
Q3 2018
11/1/2018
1275.00-0.64-2.56NA
Q2 2018
8/2/2018
1469.00-0.54-2.16NA
Q1 2018
5/3/2018
1671.00-0.56-2.24NA
Q4 2017
3/1/2018
2351.00-0.96-3.84NA
Q3 2017
11/2/2017
1209.00-1.34-5.36NA
Q2 2017
8/3/2017
1128.00-2.53-10.12NA
Q1 2017
5/11/2017
407.00-4.57-18.28NA
Q4 2016
3/8/2017
646.00-4.68-18.72NA
Q3 2016
11/3/2016
8700.00-6.00-24.00NA
Q2 2016
8/4/2016
12735.00-6.30-25.20NA
CBIO PE History Chart
PeriodPriceGAAPTTMPE
Q2 2026
7/30/2026
15.02-0.74-5.45NA
Q1 2026
4/29/2026
20.94-0.70-5.98NA
Q4 2025
2/26/2026
12.35-4.01-5.28NA
Q3 2025
11/6/2025
13.10-1.27-6.20NA
Q2 2025
7/31/2025
12.42-4.93-4.93NA
Q3 2022
11/14/2022
145.00-0.16-1.45NA
Q2 2022
8/15/2022
84.00-0.18-2.09NA
Q1 2022
5/9/2022
62.00-0.46-2.55NA
Q4 2021
3/31/2022
114.00-0.65-2.88NA
Q3 2021
11/12/2021
213.00-0.80-3.09NA
Q2 2021
8/5/2021
215.00-0.64-3.02NA
Q1 2021
5/6/2021
230.00-0.79-3.34NA
Q4 2020
3/4/2021
297.00-0.86-2.83NA
Q3 2020
11/5/2020
305.00-0.73-3.20NA
Q2 2020
8/6/2020
388.00-0.96-3.53NA
Q1 2020
5/11/2020
313.00-0.28-3.72NA
Q4 2019
2/20/2020
421.00-1.23-4.70NA
Q3 2019
11/7/2019
596.00-1.06-4.38NA
Q2 2019
8/1/2019
925.00-1.15-3.96NA
Q1 2019
5/2/2019
1194.00-1.26-3.35NA
Q4 2018
3/7/2019
1101.00-0.91-2.65NA
Q3 2018
11/1/2018
1275.00-0.64-2.70NA
Q2 2018
8/2/2018
1469.00-0.54-3.40NA
Q1 2018
5/3/2018
1671.00-0.56-5.39NA
Q4 2017
3/1/2018
2351.00-0.96-9.40NA
Q3 2017
11/2/2017
1209.00-1.34-13.12NA
Q2 2017
8/3/2017
1128.00-2.53-17.78NA
Q1 2017
5/11/2017
407.00-4.57-21.55NA
Q4 2016
3/8/2017
646.00-4.68NANA
Q3 2016
11/3/2016
8700.00-6.00NANA
Q2 2016
8/4/2016
12735.00-6.30NANA
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Crescent Biopharma (CBIO) is categorized under the Healthcare sector; to help you further research PE history across stocks, below are some other companies in the same sector:

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How should the CBIO historical PE ratio be determined?
Realizing that PE stands for Price to Earnings ratio, we need two values to compute it: stock price and earnings per share. The stock price at any given date is a known historical value, but what about the earnings number to use?

✔️Accepted answer: There are a number of different approaches when it comes to calculating a historical PE ratio for a company like Crescent Biopharma. We like to take our measurements on each of the past quarterly earnings reports. That only leaves the question of whether the earnings number at that quarterly report should be used on an annualized basis, or some other method. We approach this question using three different methods, on this CBIO Historical PE Ratio page.

What is the average historical PE for CBIO based on annualized quarterly earnings?
As we look back through earnings history, what is the resulting PE calculation if at each measurement period we use that quarter's earnings result annualized?

✔️Accepted answer: The CBIO historical PE ratio using the annualized quarterly earnings method works out to NA.

What is the average historical PE for CBIO based on trailing twelve month earnings?
As we look back through earnings history, what is the resulting PE calculation if at each measurement period we use the trailing twelve months combined earnings result in the calculation?

✔️Accepted answer: The CBIO historical PE ratio using the TTM earnings method works out to NA.

On this page we presented the CBIO Historical PE Ratio information for Crescent Biopharma' stock. The average CBIO historical PE based on using the annualized quarterly earnings result at each measurement period (for the "E" in the PE calculation; and the closing price on earnings date as the "P") is NA. Meanwhile, using the trailing twelve month (TTM) quarterly earnings result as our method of calculation the "E" value at each measurement period, the average CBIO historical PE based on this TTM earnings result method is NA. Note: any PE calculations involving negative earnings were discarded as not meaningful.

Let's now compare this CBIO historical PE result, against the recent PE: when this page was posted on 7/30/2026, the most recent closing price for CBIO had been 15.02, and the most recent quarterly earnings result, annualized, was NA. Meanwhile, the most recent TTM earnings summed to NA.

For self directed investors doing their due diligence on CBIO or any other given stock, valuation analysis for CBIO can greatly benefit from studying the past earnings and resulting PE calculations. This exercise can help inform an analysis as to whether the past earnings trajectory and current versus historical PE ratios justify the current stock value.

That's why we bring you HistoricalPERatio.com to make it easy for investors to investigate Crescent Biopharma PE history or the past PE information for any stock in our coverage universe. And in your continued research we hope you will be sure to check out the further links included for earnings surprises history (beat/miss data) as well as next earnings dates for CBIO. Thanks for visiting, and the next time you need to research CBIO Historical PE Ratio or the ratio for another stock, we hope you'll think of our site, as your go-to historical PE ratio research resource of choice.
 

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