Mersana Therapeutics Historical PE Ratio image   This MRSN PE ratio history page last updated 1/22/2026
Mersana Therapeutics Historical PE Ratio Chart
PeriodPriceGAAPAnnualizedPE
Q3 2025
11/14/2025
27.92-1.51-6.04NA
Q2 2025
8/13/2025
6.81-4.08-16.32NA
Q1 2025
5/15/2025
7.88-4.75-19.00NA
Q4 2024
3/3/2025
12.00-2.75-11.00NA
Q3 2024
11/13/2024
65.75-2.25-9.00NA
Q2 2024
8/13/2024
33.75-5.00-20.00NA
Q1 2024
5/9/2024
61.63-4.00-16.00NA
Q4 2023
2/28/2024
121.25-4.00-16.00NA
Q3 2023
11/7/2023
33.50-8.75-35.00NA
Q2 2023
8/8/2023
30.75-11.75-47.00NA
Q1 2023
5/9/2023
200.00-13.00-52.00NA
Q4 2022
2/28/2023
151.50-11.00-44.00NA
Q3 2022
11/7/2022
166.00-15.25-61.00NA
Q2 2022
8/8/2022
131.25-13.75-55.00NA
Q1 2022
5/9/2022
79.50-14.75-59.00NA
Q4 2021
2/28/2022
109.75-17.00-68.00NA
Q3 2021
11/9/2021
238.00-15.75-63.00NA
Q2 2021
8/6/2021
309.25-14.75-59.00NA
Q1 2021
5/10/2021
373.00-12.50-50.00NA
Q4 2020
2/26/2021
454.50-10.50-42.00NA
Q3 2020
11/9/2020
573.00-8.25-33.00NA
Q2 2020
8/7/2020
506.75-8.25-33.00NA
Q1 2020
5/8/2020
245.25-8.75-35.00NA
Q4 2019
2/28/2020
216.50-8.50-34.00NA
Q3 2019
11/6/2019
49.50-8.75-35.00NA
Q2 2019
8/8/2019
79.00-9.00-36.00NA
Q1 2019
5/9/2019
147.7517.5070.002.1
Q4 2018
3/8/2019
113.00-24.25-97.00NA
Q3 2018
11/13/2018
151.00-18.75-75.00NA
Q2 2018
8/14/2018
322.75-13.50-54.00NA
Q1 2018
5/14/2018
412.75-13.50-54.00NA
Q4 2017
3/28/2018
398.00-15.25-61.00NA
Q3 2017
11/9/2017
427.50-8.75-35.00NA
Q2 2017
8/11/2017
385.50-158.25-633.00NA
Mersana Therapeutics PE History Chart
PeriodPriceGAAPTTMPE
Q3 2025
11/14/2025
27.92-1.51-13.09NA
Q2 2025
8/13/2025
6.81-4.08-13.83NA
Q1 2025
5/15/2025
7.88-4.75-14.75NA
Q4 2024
3/3/2025
12.00-2.75-14.00NA
Q3 2024
11/13/2024
65.75-2.25-15.25NA
Q2 2024
8/13/2024
33.75-5.00-21.75NA
Q1 2024
5/9/2024
61.63-4.00-28.50NA
Q4 2023
2/28/2024
121.25-4.00-37.50NA
Q3 2023
11/7/2023
33.50-8.75-44.50NA
Q2 2023
8/8/2023
30.75-11.75-51.00NA
Q1 2023
5/9/2023
200.00-13.00-53.00NA
Q4 2022
2/28/2023
151.50-11.00-54.75NA
Q3 2022
11/7/2022
166.00-15.25-60.75NA
Q2 2022
8/8/2022
131.25-13.75-61.25NA
Q1 2022
5/9/2022
79.50-14.75-62.25NA
Q4 2021
2/28/2022
109.75-17.00-60.00NA
Q3 2021
11/9/2021
238.00-15.75-53.50NA
Q2 2021
8/6/2021
309.25-14.75-46.00NA
Q1 2021
5/10/2021
373.00-12.50-39.50NA
Q4 2020
2/26/2021
454.50-10.50-35.75NA
Q3 2020
11/9/2020
573.00-8.25-33.75NA
Q2 2020
8/7/2020
506.75-8.25-34.25NA
Q1 2020
5/8/2020
245.25-8.75-35.00NA
Q4 2019
2/28/2020
216.50-8.50-8.75NA
Q3 2019
11/6/2019
49.50-8.75-24.50NA
Q2 2019
8/8/2019
79.00-9.00-34.50NA
Q1 2019
5/9/2019
147.7517.50-39.00NA
Q4 2018
3/8/2019
113.00-24.25-70.00NA
Q3 2018
11/13/2018
151.00-18.75-61.00NA
Q2 2018
8/14/2018
322.75-13.50-51.00NA
Q1 2018
5/14/2018
412.75-13.50-195.75NA
Q4 2017
3/28/2018
398.00-15.25NANA
Q3 2017
11/9/2017
427.50-8.75NANA
Q2 2017
8/11/2017
385.50-158.25NANA
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Mersana Therapeutics (MRSN) is categorized under the Healthcare sector; to help you further research PE history across stocks, below are some other companies in the same sector:

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How should the MRSN historical PE ratio be determined?
Realizing that PE stands for Price to Earnings ratio, we need two values to compute it: stock price and earnings per share. The stock price at any given date is a known historical value, but what about the earnings number to use?

✔️Accepted answer: There are a number of different approaches when it comes to calculating a historical PE ratio for a company like Mersana Therapeutics. We like to take our measurements on each of the past quarterly earnings reports. That only leaves the question of whether the earnings number at that quarterly report should be used on an annualized basis, or some other method. We approach this question using three different methods, on this MRSN Historical PE Ratio page.

What is the average historical PE for MRSN based on annualized quarterly earnings?
As we look back through earnings history, what is the resulting PE calculation if at each measurement period we use that quarter's earnings result annualized?

✔️Accepted answer: The MRSN historical PE ratio using the annualized quarterly earnings method works out to 2.1.

What is the average historical PE for MRSN based on trailing twelve month earnings?
As we look back through earnings history, what is the resulting PE calculation if at each measurement period we use the trailing twelve months combined earnings result in the calculation?

✔️Accepted answer: The MRSN historical PE ratio using the TTM earnings method works out to NA.

On this page we presented the Mersana Therapeutics Historical PE Ratio information for Mersana Therapeutics' stock. The average MRSN historical PE based on using the annualized quarterly earnings result at each measurement period (for the "E" in the PE calculation; and the closing price on earnings date as the "P") is 2.1. Meanwhile, using the trailing twelve month (TTM) quarterly earnings result as our method of calculation the "E" value at each measurement period, the average MRSN historical PE based on this TTM earnings result method is NA. Note: any PE calculations involving negative earnings were discarded as not meaningful.

Let's now compare this MRSN historical PE result, against the recent PE: when this page was posted on 1/6/2026, the most recent closing price for MRSN had been 29.08, and the most recent quarterly earnings result, annualized, was 70. Meanwhile, the most recent TTM earnings summed to NA. From these numbers, we calculate the recent MRSN PE on 1/6/2026 based on annualized quarterly EPS was 0.4. Based on MRSN's history, that recent PE is low relative to the historical average, with the recent PE 81.0% lower than the historical average PE across our data set for Mersana Therapeutics.

For self directed investors doing their due diligence on MRSN or any other given stock, valuation analysis for MRSN can greatly benefit from studying the past earnings and resulting PE calculations. This exercise can help inform an analysis as to whether the past earnings trajectory and current versus historical PE ratios justify the current stock value.

That's why we bring you HistoricalPERatio.com to make it easy for investors to investigate Mersana Therapeutics PE history or the past PE information for any stock in our coverage universe. And in your continued research we hope you will be sure to check out the further links included for earnings surprises history (beat/miss data) as well as next earnings dates for MRSN. Thanks for visiting, and the next time you need to research MRSN Historical PE Ratio or the ratio for another stock, we hope you'll think of our site, as your go-to historical PE ratio research resource of choice.

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